This is not an entire list of feasible Negative effects. Should you discover other side effects not listed higher than, Get hold of your medical professional or pharmacist.
Codeine causes a reduction in motility related with an increase in sleek muscle tone within the antrum on the abdomen and duodenum. Digestion of foods from the small intestine is delayed and propulsive contractions are reduced.
Codeine makes peripheral vasodilation which can end in orthostatic hypotension or syncope. Manifestations of histamine release and/or peripheral vasodilation may perhaps involve pruritus, flushing, purple eyes and perspiring and/or orthostatic hypotension.
Promethazine with Codeine Oral Solution incorporates promethazine, a phenothiazine. Phenothiazines are involved with dystonic reactions, specially in pediatric clients who definitely have an acute ailment connected with dehydration.
Sedating medication may bring about confusion and around-sedation in the aged; elderly individuals usually should be started on very low doses of promethazine with codeine syrup and observed closely.
Though it can help Lots of people, this medication contains a threat for abuse and could often cause habit. This risk can be greater In case you have a substance use problem (which include overuse of or addiction to prescription drugs/Liquor).
Promethazine hydrochloride and codeine phosphate really should be provided to the Expecting lady only if Evidently desired.
*Normal and up to financial savings percentages are based on all discounted prescriptions that were run with the WellRx system in 2022. Price reduction percentages characterize savings supplied off click here of pharmacies’ retail rates for people who do not need a reduction software and shell out money.
However, When your mouth proceeds to really feel dry for in excess of two months, Check out with your clinical health care provider or dentist. Continuing dryness of your mouth may raise the prospect of dental disease, which includes tooth decay, gum disorder, and fungus bacterial infections .
Promethazine is properly absorbed with the gastrointestinal tract. Scientific consequences are evident within 20 minutes immediately after oral administration and generally very last 4 to six hrs, Whilst they may persist assuming that 12 hours.
Employing this medication with any of the subsequent medicines will likely be not suggested, but could possibly be expected occasionally. If both medicines are prescribed together, your medical doctor may possibly change the dose or how often you use one particular or both equally with the medicines.
Stay clear of the use of promethazine hydrochloride and codeine phosphate oral Alternative in adolescents 12 to eighteen many years of age who produce other risk things that will increase their sensitivity on the respiratory depressant effects of codeine.
Lengthy-phrase animal scientific studies have not been performed to evaluate the carcinogenic opportunity of codeine or of promethazine, nor are there other animal or human data about carcinogenicity, mutagenicity, or impairment of fertility with these brokers.
four)]. Observational scientific studies have shown that concomitant usage of opioid analgesics and benzodiazepines raises the threat of drug-related mortality in comparison with usage of opioids by itself. Due to very similar pharmacologic Homes, it's affordable to anticipate equivalent possibility with concomitant utilization of opioid cough medicines and benzodiazepines, other CNS depressants, or Alcoholic beverages.